Department of Obstetrics and Gynecology

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Maternal-Fetal Medicine

Welcome to the Division of Maternal-Fetal Medicine

Tripartite Mission

The Maternal-Fetal Medicine Division is actively involved in each of the Department of Obstetrics and Gynecology's clinical, research and educational missions, striving to bring evidenced-based, compassionate, quality care to the women of Indiana.

The MFM Division is currently composed of six MFM members, two hospitalists, one clinical research director, and one laboratory PhD director. The faculty physicians provide inpatient and outpatient consultation as well as primary comprehensive care of high-risk pregnancies, fetal ultrasound, prenatal diagnosis and invasive fetal treatment. We are affiliated with the IU Health network of Hospitals and Riley Children's Hospital, one of the top children's hospitals in the United States.

The Maternal-Fetal Physician group operates as an integrated group serving referring providers at three IU Health Hospitals throughout the Indianapolis metropolitan area and the Eskenazi Hospital on campus. The combined annual deliveries for the integrated system exceed 7,000. The IU MFM group and the Level 3 NICU at Riley also serve as the tertiary care referral network of physicians providing outpatient consultative services at several other hospitals in central Indiana.

Our Team:

Our Clinical Strengths and Expertise

The Division offers a full range of diagnostic and treatment options for the women of Indiana. Some of the services include:

Management of the Diabetic Pregnancy

The Maternal-Fetal Medicine specialists manage more diabetic pregnancies than any other physician group in the state of Indiana. Our physicians are highly skilled at working with diabetic patients to ensure that they have the healthiest possible pregnancy and baby.

Management of the High-Risk Pregnancy

Our Maternal-Fetal Medicine physicians are well trained to manage many types of high-risk pregnancies. They manage and deliver more high-risk pregnancies than any other group of physicians in the state of Indiana.

High-Resolution Ultrasound

Our Maternal-Fetal Medicine doctors use an advanced, highly sensitive, ultrasound that will allow them to detect certain birth defects. You may be referred to one of our high-risk obstetricians for a High-Resolution Ultrasound if your primary OB/GYN physician believes that a specialist would be better able to evaluate and manage your pregnancy.

Genetic Amniocentesis

Amniocentesis is a procedure in which a small sample of amniotic fluid (the fluid surrounding your baby) is withdrawn from the uterus using a fine needle that is guided by ultrasound. The fluid contains cells from the baby that can be analyzed to detect a variety of genetic problems. Amniotic fluid contains Alpha-Fetoprotein (AFP), and the analysis of AFP allows physicians to screen for neural tube defects, ventral wall defects, and high-risk pregnancies.

Chorionic Villi Sampling (CVS)

CVS is diagnostic test used early in a woman's pregnancy. With CVS, the doctor will remove a small amount of the villi (tissue that will eventually become the placenta) from your womb. The villi will be analyzed to screen for certain chromosomal or genetic problems that can be diagnosed in your baby. The doctor will use a fine needle to obtain the villi, and the needle will either be inserted into your abdomen or vagina to access the womb.

Maternal Serum Alpha-Fetoprotein (MS-AFP) Testing Services

Most general obstetricians order an AFP test in the early portion of a woman's pregnancy. If the AFP test demonstrates that you have elevated AFP levels, it may indicate that your baby has certain birth defects. At IUH Women's Healthcare, our high-risk obstetricians will work with your primary OB/GYN to analyze your AFP test and recommend additional tests that will help to determine the health of your baby.

Percutaneous Umbilical Blood Sampling (PUBS)

PUBS is a very new diagnostic test during which the doctor will remove a small amount of blood from the umbilical cord of your baby.  A wide variety of diagnostic tests can be performed using the umbilical cord blood sample. PUBS may also be used if your baby requires a blood transfusion while he/she is still in your uterus. Using an ultrasound machine and a fine needle, the doctor can transfuse your baby's umbilical cord with blood if it is needed.

First Trimester freeBeta/PAPP-A/NT Testing

This test is available to women during their first trimester of pregnancy (10 weeks 4 days - 13 weeks 3 days) and is used to help identify babies who may be at risk for Down syndrome or Trisomy 18. The test involves both blood testing and a special ultrasound exam to help determine your baby's risk for birth defects.

Preconceptual and Genetic Counseling

Genetic counselors are Master's prepared individuals who work with couples to understand the concerns associated with the occurrence, or the chance of occurrence, of a birth defect in a family. Genetic counselors help you to understand the medical facts, understand how a birth defect may be carried in a family, understand how to lower the risk of birth defects in a family, and make informed decisions about your pregnancy and the possibility that your baby may have birth defects.

Our Research

The MFM Division has a record of ongoing production of basic science, clinical/translational and epidemiologic research, including membership in the Consortium on Safe Labor, Obstetric-Fetal Pharmacology Research Units Network and Nulliparous Network of the NICHD. In addition, we have long-standing partnerships with the prestigious Regenstrief Institute for informatics and healthcare research in Indianapolis.

The Division supports a Perinatal Epigenetics Research Laboratory that conducts cutting-edge translational research in gene-environment interactions that affect fetal development, maternal health and postnatal health trajectories. The Lab supports the research training of residents and fellows and collaborations with other campus investigators including those in the Wells Pediatric Research Center and IU Simon Cancer Center.

Another important component of the Division is the Pregmed ( program. Supported by NIH funding, the focus of PregMed is to develop personalized therapeutic approaches for pregnant women and children using cutting-edge analytic, genomic, and computational techniques.

The Obstetric Clinical Pharmacology Lab, directed by Dr. Quinney, provides laboratory space and resources to conduct a variety of basic and translational study techniques related to therapeutics in pregnant women.  Equipment and expertise is available to conduct a variety of experimental techniques, including cell culture; molecular biology; pharmacogenomic and gene expression analyses; in vitro drug metabolism assays; analytical drug assays; and pharmacokinetic-pharmacodynamic modeling.  This laboratory also serves as a resource to support the analysis of clinical study samples. 


The Division participates fully in the education of the 40 OB/GYN residents and 280 medical students of the IU School of Medicine. The MFM physicians interact directly with residents through a specific high-risk rotation. Residents learn to care for women with complicated and high-risk pregnancies in both the outpatient consultative clinic and on Labor and Delivery suites at several hospitals.

The Division has an accredited Fellowship program in Maternal-Fetal Medicine. The Fellowship strives to cultivate the next generation of Maternal-Fetal Medicine (MFM) practitioners to fill a regional shortage of perinatologists and arm them with the necessary skills to independently care for pregnant women with multiple medical and obstetrical problems in the rural communities of the Midwest. We are also committed to training new MFM specialists with the academic expertise to become future leaders in the field.

To Contact Us:

Frank Schubert, MD, MS
Interim Division Director

For office numbers and sites where you can receive care, please access:

Indiana University School of Medicine
Department of Obstetrics and Gynecology
550 University Blvd
Indianapolis, IN 46202

A gift to the department of Obstetrics and Gynecology can be made online through our Gift Development Department or through the mail with a linked PDF Form.


Thank you for making a difference!

For information about the various ways to give or on unique procedures we perform, please contact us at 317-944-8609.